The processes required for life as we know it are carried out by protein and nucleic acid catalysts that act as molecular machines. Many aspects of research in our department touch upon these machines, how they are assembled, activated, remodeled or damaged.
Faculty with a research interest in molecular machines:
- Elliott Crooke [Professor]
Initiation of DNA replication.
- Jessica Jones [Associate Professor]
V(D)J recombination; ubiquitin conjugation.
- Mary Beth Martin [Professor]
Conformational changes in estrogen receptor.
- Hiroshi Nakai [Professor]
Coordination of DNA replication, recombination, and repair; molecular chaperones; transposition.